Nanoparticulate compositions comprising a drug and...

Details Nanoparticulate compositions comprising a drug and... Nanoparticulate compositions comprising a drug and...

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 47/32 (2006.01)

Patent

CA 2428785

The present invention is directed to nanoparticulate compositions comprising a poorly soluble drug and at least one copolymer of vinyl pyrrolidone and vinyl acetate as a surface stabilizer adsorbed to the surface of the drug. Also encompassed by the invention are pharmaceutical compositions comprising a nanoparticulate composition of the invention, methods of making and using such nanoparticulate and pharmaceutical compositions.

La présente invention concerne des compositions nanoparticulaires comprenant un médicament peu soluble et au moins un copolymère de pyrrolidone de vinyle et d'acétate de vinyle en tant que stabilisateur de surface adsorbé à la surface du médicament. L'invention concerne en outre des compositions pharmaceutiques comprenant une composition nanoparticulaire de l'invention, ainsi que des méthodes de production et d'utilisation desdites compositions nanoparticulaires et pharmaceutiques.

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