Nanoparticulate compositions of angiogenesis inhibitors

Details Nanoparticulate compositions of angiogenesis inhibitors Nanoparticulate compositions of angiogenesis inhibitors

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 31/565 (2006.01)

Patent

CA 2479665

Nanoparticulate compositions comprising at least one poorly soluble angiogenesis inhibitor and at least one surface stabilizer are described. The nanoparticulate compositions have an average particle size of less than about 2000 nm. The invention also describes methods of making and using such compositions.

La présente invention concerne des compositions nanoparticulaires comprenant au moins un inhibiteur d'angiogenèse faiblement soluble et au moins un stabilisateur de surface. Lesdites compositions nanoparticulaires présentent une granulométrie moyenne inférieure à environ 2000 nm. L'invention concerne également des méthodes de fabrication et d'utilisation desdites compositions.

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