Nanoparticulate compositions of angiogenesis inhibitors

Details Nanoparticulate compositions of angiogenesis inhibitors Nanoparticulate compositions of angiogenesis inhibitors

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 31/565 (2006.01)

Patent

CA 2718189

Nanoparticulate compositions comprising at least one poorly soluble angiogenesis inhibitor and at least one surface stabilizer are described. The nanoparticulate compositions have an average particle size of less than about 2000 nm. The invention also describes methods of making and using such compositions.

Linvention concerne des compositions de nanoparticules comprenant au moins un inhibiteur dangiogenèse médiocrement soluble et au moins un stabilisateur de surface. Les compositions de nanoparticules ont une taille moyenne de particule inférieure à environ 2 000 nm. Linvention décrit également des procédés de préparation et dutilisation de telles compositions.

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