Nanoparticulate compositions of map kinase inhibitors

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/00 (2006.01) A61K 9/14 (2006.01) A61K 31/473 (2006.01) A61K 31/551 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2479737

Nanoparticulate compositions comprising at least one poorly soluble MAP kinase inhibitor and at least one surface stabilizer are described. The nanoparticulate compositions have an average particle size of less than about 2000 nm. The invention also describes methods of making and using such compositions.

L'invention concerne des compositions nanoparticulaires comprenant au moins un inhibiteur de la MAP kinase peu soluble et au moins un stabilisateur de surface. Les compositions nanoparticulaires présentent une granulométrie moyenne inférieure à environ 2 000 nm. L'invention concerne également des procédés d'obtention et d'utilisation de telles compositions.

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