Nanoparticulate corticosteroid and antihistamine formulations

A - Human Necessities – 61 – K

Patent

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A61K 9/16 (2006.01) A61K 9/51 (2006.01) A61K 31/00 (2006.01)

Patent

CA 2602341

Compositions comprising a nanoparticulate corticosteroid and an antihistamine are described. The compositions are useful in the prophylaxis and chronic treatment of asthma in adults and pediatric patients and for the relief of allergic conjunctivitis, symptoms of seasonal allergic rhinitis in adults and pediatric patients. Combining an antihistamine with a nanoparticulate corticosteroid in a single formulation results in improved efficacy.

L'invention concerne des compositions contenant un corticostéroïde nanoparticulaire et un antihistamine. Ces compositions sont utiles pour la prévention et le traitement chronique de l'asthme chez les adultes et les enfants et pour le soulagement de conjonctivites allergiques, des symptômes de rhinite allergique saisonnière chez les adultes et les enfants. La combinaison d'un antihistamine et d'un corticostéroïde nanoparticulaire dans une formulation unique entraîne une amélioration de l'efficacité.

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