Nanoparticulate fibrate formulations

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/216 (2006.01) A61K 9/14 (2006.01) A61K 45/06 (2006.01) A61K 47/14 (2006.01) A61K 47/38 (2006.01) A61P 3/06 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2487054

The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective average particle size of less than about 2000 nm.

La présente invention concerne des compositions de fibrate présentant des profils pharmacocinétiques améliorés et une variabilité réduite selon que le patient est à jeun ou non. Les particules de fibrate de la composition ont une taille effective moyenne inférieure à 2000 nm environ.

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