A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/51 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 31/185 (2006.01) A61K 31/216 (2006.01) A61K 31/366 (2006.01) A61K 31/40 (2006.01) A61K 31/4025 (2006.01) A61K 31/405 (2006.01) A61K 31/4164 (2006.01) A61K 31/44 (2006.01) A61K 45/06 (2006.01) A61P 3/06 (2006.01) A61P 9/00 (2006.01) A61P 9/08 (2006.01) A61P 9/10 (2006.01) A61P 41/00 (2006.01) A61P 43/00 (2006.01)
Patent
CA 2488499
The present invention is directed to nanoparticulate compositions comprising statin such as lovastatin or simvastatin including surface stabilizer. The statin particles of the composition have an effective average particle size of less than about 2000 nm. In another aspect of this invention, novel combinations of statins and other cholesterol lowering agents are described and methods of using same are taught.
L'invention concerne des compositions nanoparticulaires qui contiennent de la statine de type lovastatine ou simvastatine comprenant un agent de stabilisation de surface. Les particules de statine de la composition présente une taille moyenne particulaire effective inférieure à environ 2000 nm. L'invention concerne, selon un autre aspect, des nouvelles combinaisons de statines et d'autres hypocholestérolémiants ainsi que des procédés d'utilisation associés.
Cary Greta
Cooper Eugene R.
Hovey Douglas
Lindner Marie
Liversidge Elaine
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Elan Pharma International Ltd.
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