Nanoreporters and methods of manufacturing and use thereof

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2640385

The present invention relates to compositions and methods for detection and quantification of individual target molecules in biomolecular samples. In particular, the invention relates to coded, labeled probes that are capable of binding to and identifying target molecules based on the probes' label codes. Methods of making and using such probes are also provided. The probes can be used in diagnostic, prognostic, quality control and screening applications.

L'invention concerne des compositions et des procédés permettant la détection et la quantification de molécules cibles individuelles dans des échantillons biomoléculaires, et en particulier des sondes marquées et codées, capables de se fixer sur des molécules cibles et de les identifier au moyen de codes associés à leur marquage. L'invention concerne en outre des procédés de production et d'utilisation de ces sondes. Ces sondes conviennent pour des applications de diagnostic, de pronostic, de contrôle de qualité et de criblage.

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