Naphthalene derivative and processes for preparing same

Details Naphthalene derivative and processes for preparing same Naphthalene derivative and processes for preparing same

C - Chemistry, Metallurgy

07

C

167/179, 260/295

C07C 69/94 (2006.01) A61K 31/235 (2006.01) C07D 213/02 (2006.01) C07D 213/64 (2006.01) C07D 295/088 (2006.01)

Patent

CA 1294278

Abstract: The present invention is directed to naphthalene derivatives of the formula: Image (I) wherein Ring A is a substituted or unsubstituted benzene ring; each of R1 and R2 is a group of the formula: -OR5, -NHR5 or Image ; or either one of R1 and R2 is a lower alkoxy group and the other one is a group of the formula: -OR5, -NHR5 or Image ; each of R3 and R4 is a lower alkoxy group, or one of R3 and R4 is a lower alkoxy group and the other is a hydrogen atom; R5 is a substituted alkyl group, a heterocyclic group, a cyclo- alkyl group, an alkyl group of at least 5 carbon atoms or alkenyl group; and each of R6 and R7 is a hydrogen atom or a lower alkyl group and salts thereof. These naphthalene derivatives (I) and their salts have excellent hypolipidemic activity and are useful for the treatment or prophylaxis of hyperlipidemia and/or arteriosclerosis.

540829

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