Naphthalene derivatives, process for their preparation and...

C - Chemistry – Metallurgy – 07 – C

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C07C 35/22 (2006.01) A61K 31/045 (2006.01) A61K 31/22 (2006.01) A61K 31/335 (2006.01) C07C 35/36 (2006.01) C07C 35/37 (2006.01) C07C 43/184 (2006.01) C07C 69/00 (2006.01) C07C 69/013 (2006.01) C07C 69/21 (2006.01) C07D 303/12 (2006.01) C07D 303/16 (2006.01) C07D 307/77 (2006.01) C07D 307/92 (2006.01)

Patent

CA 2129906

PRECIS Composés de formule (I): Image (I) dans laquelle: - R1, R'1 et R2 sont choisis indépendamment l'un de l'autre parmi l'hydrogène etun radical alkyle, les deux groupements R2 étant en position "cis" par rapport aux cycles, - et R, R3, R4, R5, R6, R7, R8, R9, R10, R'a et R'b sont tels que définis dans la description. Ces composés trouvent leur application en thérapeutique dans le traitement du diabète de l'insulinorésistance, des maladies cardiovasculaires et des insulinomes.

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