Naphthalenecarboxamides as tachykinin receptor antagonists

Details Naphthalenecarboxamides as tachykinin receptor antagonists Naphthalenecarboxamides as tachykinin receptor antagonists

A - Human Necessities

61

K

A61K 31/445 (2006.01) C07D 211/18 (2006.01) C07D 211/24 (2006.01) C07D 211/26 (2006.01) C07D 211/28 (2006.01) C07D 211/34 (2006.01) C07D 211/58 (2006.01) C07D 211/66 (2006.01) C07D 211/76 (2006.01) C07D 401/04 (2006.01) C07D 401/10 (2006.01) C07D 401/14 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2344807

A compound having formula (Ia) and any pharmaceutically-acceptable salt thereof, and their use for treating depression, anxiety, asthma, rheumatoid arthritis, Alzheimer's disease, cancer, schizophrenia, oedema, allergic rhinitis, inflammation, pain, gastrointestinal-hypermotility, anxiety, emesis, Huntington's disease, psychoses including depression, hypertension, migraine, bladder hypermotility, or urticaria and compositions including such compounds and processes for making the compounds.

L'invention se rapporte à un composé représenté par la formule (Ia), à tout sel pharmaceutiquement acceptable de ce composé ainsi qu'à leur utilisation pour traiter la dépression, l'anxiété, l'asthme, la polyarthrite rhumatoïde, la maladie d'Alzheimer, le cancer, la schizophrénie, les oedèmes, la rhinite allergique, les inflammations, la douleur, l'hypermotilité gastro-intestinale, l'anxiété, les vomissements, la chorée de Huntington, les psychoses du type dépression, hypertension, migraine, hypermotilité de la vessie, ou l'urticaire. L'invention se rapporte également à des compositions pharmaceutiques contenant ces composés et à des procédés de fabrication de ces composés.

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