C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/289
C07D 215/14 (2006.01) C07D 213/30 (2006.01) C07D 235/12 (2006.01) C07D 277/24 (2006.01) C07D 277/64 (2006.01)
Patent
CA 1331001
ABSTRACT The invention concerns .alpha.-methyl-6-(2-quinolinyl- methoxy)-2-naphthalene acetic acid, amine salts wherein the amine is an hydroxyalkylamine of formula NR1R2R3 wherein R1 is hydrogen, phenyl, alkyl of 1-6 carbon atoms or hydroxyalkyl of 1-6 carbon atoms, R2 is hydrogen, alkyl of 1-6 carbon atoms or hydroxyalkyl of 1-6 carbon atoms and R3 is hydroxyalkyl of 1-12 carbon atoms. The preferred salts are the tromethamine salts. The amine salts have enhanced activity as compared to the parent acids.
613074
Bicksler James J.
Giberson John W.
Kreft Anthony F. III
Kubrak Dennis M.
Musser John H.
American Home Products Corporation
Ridout & Maybee Llp
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