Naphthaline derivatives useful as histamine-3-receptor ligands

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 401/12 (2006.01) A61K 31/40 (2006.01) A61K 31/4025 (2006.01) A61K 31/454 (2006.01) A61K 31/4545 (2006.01) A61K 31/4725 (2006.01) A61K 31/497 (2006.01) A61K 31/5377 (2006.01) A61K 31/541 (2006.01) C07D 207/06 (2006.01) C07D 211/16 (2006.01) C07D 211/46 (2006.01) C07D 217/06 (2006.01) C07D 241/04 (2006.01) C07D 295/088 (2006.01) C07D 295/192 (2006.01)

Patent

CA 2566526

The present invention relates to compounds of formula (I) wherein A, R1 and R2 are as defined in the description and claims, and pharmaceutically acceptable salts thereof, to the preparation of such compounds and pharmaceutical compositions containing them. The compounds are useful for the treatment and/or prevention of diseases which are associated with the modulation of H3 receptors.

La présente invention se rapporte à des composés de la formule (1) dans laquelle A, R?1¿ et R?2¿ sont tels que définis dans la description et les revendications, et à des sels pharmaceutiquement acceptables de ces derniers, à la préparation desdits composés et à des compositions pharmaceutiques les contenant. Les composés de l'invention sont utilisés dans le traitement et/ou la prévention de maladies qui sont associées à une modulation des récepteurs H3.

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