A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/179, 260/396
A61K 31/12 (2006.01) C07C 46/00 (2006.01) C07C 50/24 (2006.01) C07C 50/32 (2006.01) C07C 69/157 (2006.01) C07C 217/12 (2006.01) C07C 225/30 (2006.01) C07C 229/60 (2006.01)
Patent
CA 1329621
ABSTRACT The present invention relates to the use of known and novel naphthoquinones in the treatment and prophylaxis of Pneumocystis carinii infections, and for the manufacture of medicaments for the treatment and prophylaxis of P.carinii infections, novel formulations containing said compounds, and novel naphthoquinones of formula (VI): Image (VI) wherein R11 and R12 each represent -O and the dotted line represents a double bond between the 2 and 3 positions of the quinone ring, in which case R13 represents a group -OCOR5; a group OR6 or SR6; or a group NR7R8; or the dotted line represents double bonds at the 1,2 and 3,4 positions of the quinol ring and R11, R12 and R13 each represents a group -OCO?14, wherein R14 represents an optionally substituted C1-10alkyl group.
608367
Gutteridge Winston Edward
Hudson Alan Thomas
Latter Victoria Susan
Gutteridge Winston Edward
Hudson Alan Thomas
Latter Victoria Susan
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Wellcome Foundation Limited (the)
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