Naphthothiopyranone derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 409/06 (2006.01) C07D 335/08 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2086013

ABSTRACT A naphthothiopyranone derivative represented by the formula: Image . (wherein R1 is a hydrogen atom or an alkyl group having 1 to 4 carbon atoms) and an acid addition salt thereof have more excellent antagonist effect at serotonin 3 receptors than the prior art compounds and the effects based thereon, e.g. anti-vomiting effect, gastrointes- tinal movement regulating effect and anti-anxiety effect.

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