C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 57/58 (2006.01) A61K 31/192 (2006.01) A61K 31/216 (2006.01) A61K 31/277 (2006.01) A61K 31/36 (2006.01) A61P 11/06 (2006.01) C07C 69/78 (2006.01) C07C 231/12 (2006.01) C07C 255/57 (2006.01) C07C 311/16 (2006.01) C07C 317/24 (2006.01) C07D 231/12 (2006.01) C07D 257/04 (2006.01) C07D 295/26 (2006.01) C07D 317/70 (2006.01)
Patent
CA 2740864
The invention is concerned with the compounds of formula (I) and pharmaceutically acceptable salts and esters thereof, wherein X, Q, and R1-R6 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are antagonists or partial agonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
La présente invention concerne des composés de formule I : et les sels et esters pharmaceutiquement acceptables de ceux-ci, dans lesquels X, Q, et R1-R6 sont définis dans la description détaillée et les revendications annexées. L'invention concerne également des procédés de préparation et d'utilisation des composés de formule I ainsi que des compositions pharmaceutiques les contenant. Les composés de formule I sont des antagonistes ou des agonistes partiels du récepteur CRTH2 et peuvent être utiles pour le traitement de maladies et de troubles associés à ce récepteur, tels que l'asthme.
Firooznia Fariborz
Gillespie Paul
Lin Tai-An
Mertz Eric
Sidduri Achyutharao
Borden Ladner Gervais Llp
F. Hoffmann-La Roche Ag
LandOfFree
Naphthylacetic acids does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Naphthylacetic acids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Naphthylacetic acids will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1410107