C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/228, 260/296
C07D 213/63 (2006.01) A61K 31/44 (2006.01) C07D 213/68 (2006.01) C07D 213/73 (2006.01) C07D 213/74 (2006.01) C07D 213/89 (2006.01)
Patent
CA 2019624
Abstract Naphthylamino- and naphthyloxy-pyridinamines and related compounds, a process for their preparation and their use as dermatological agents The present invention relates to compounds of the formula Image where X is O or NR1, R1 being hydrogen, loweralkyl or loweralkylcarbonyl, Y is hydrogen, loweralkyl, loweralkoxy, halogen or trifluoromethyl, Z is NO2 or NHR, where R is hydrogen, loweralkyl, arylloweralkyl or loweralkylcarbonyl, and n is O or 1, with the proviso that n is O when Z is NHR, and a process for their preparation. The compounds are useful as topical antiinflammatory agents for the treatment of skin disorders.
Davis Larry
Effland Richard C.
Klein Joseph T.
Olsen Gordon E.
Bereskin & Parr
Davis Larry
Effland Richard C.
Hoechst-Roussel Pharmaceuticals Inc.
Klein Joseph T.
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