Naphthylpyrimidine, naphthylpyrazine and naphthylpyridazine...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 239/26 (2006.01) A61K 31/506 (2006.01) A61P 25/00 (2006.01) C07D 239/34 (2006.01) C07D 401/06 (2006.01) C07D 403/04 (2006.01) C07D 451/02 (2006.01) C07D 471/04 (2006.01) C07D 471/10 (2006.01) C07D 487/04 (2006.01) C07D 487/08 (2006.01)

Patent

CA 2697100

The present invention relates to naphthylpyrimidine analogs, methods of making naphthylpyrimidine analogs, compositions comprising a naphthylpyrimidine analog, and methods for treating canonical Wnt-[beta-symbol]-catenin cellular messaging system-related disorders comprising administering to a subject in need thereof an effective amount of a naphthylpyrimidine, naphthylpyrazine and naphthylpyridazine analog.

La présente invention concerne des analogues de la naphthylpyrimidine, des procédés de fabrication d'analogues de la naphthylpyrimidine, de compositions comprenant un analogue de la naphthylpyrimidine, et des procédés de traitement de troubles canoniques liés au système de messagerie cellulaire wnt-[symbole bêta]-caténine comprenant l'administration à un sujet en ayant besoin d'une quantité efficace d'analogue de la naphthylpyrimidine, de la naphthylpyrazine et de la naphthylpyridazine.

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