Naphthyridine derivative

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 471/04 (2006.01) A61K 31/4375 (2006.01) A61K 31/439 (2006.01) A61K 31/444 (2006.01) A61K 31/4545 (2006.01) A61K 31/496 (2006.01) A61K 31/497 (2006.01) A61K 31/5377 (2006.01) A61P 11/00 (2006.01) A61P 11/06 (2006.01) A61P 11/08 (2006.01) A61P 43/00 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2385178

2-Oxo-1,2-dihydro-1,8-naphthyridine derivatives characterized by bearing a specific substituent, -X-R6, at the 3-position and a cyclic substituent, R5, at the 4-position; or salts thereof. The derivatives and the salts are useful as drugs, particularly preventive or therapeutic agents for respiratory diseases related to PDE IV.

La présente invention concerne des dérivés de 2-Oxo-1, 2-dihydro-1,8-naphthyridine caractérisés par le fait qu'ils portent un substituant spécifique, -X-R?6¿, en position 3 et un substituant cyclique, R?5¿, en position 4, ou des sels de ceux-ci. Ces dérivés et ces sels conviennent pour des médicaments, en particulier pour des agents thérapeutiques ou pour des agents de prévention des maladies respiratoires liées à la PDE IV.

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