C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/4375 (2006.01) A61K 31/439 (2006.01) A61K 31/444 (2006.01) A61K 31/4545 (2006.01) A61K 31/496 (2006.01) A61K 31/497 (2006.01) A61K 31/5377 (2006.01) A61P 11/00 (2006.01) A61P 11/06 (2006.01) A61P 11/08 (2006.01) A61P 43/00 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2385178
2-Oxo-1,2-dihydro-1,8-naphthyridine derivatives characterized by bearing a specific substituent, -X-R6, at the 3-position and a cyclic substituent, R5, at the 4-position; or salts thereof. The derivatives and the salts are useful as drugs, particularly preventive or therapeutic agents for respiratory diseases related to PDE IV.
La présente invention concerne des dérivés de 2-Oxo-1, 2-dihydro-1,8-naphthyridine caractérisés par le fait qu'ils portent un substituant spécifique, -X-R?6¿, en position 3 et un substituant cyclique, R?5¿, en position 4, ou des sels de ceux-ci. Ces dérivés et ces sels conviennent pour des médicaments, en particulier pour des agents thérapeutiques ou pour des agents de prévention des maladies respiratoires liées à la PDE IV.
Iwata Masahiro
Kawano Noriyuki
Kobayashi Miki
Shiraki Ryota
Takeuchi Makoto
Astellas Pharma Inc.
Dennison Associates
Yamanouchi Pharmaceutical Co. Ltd.
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