Naphthyridines which affect il-4 and g-csf

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 471/04 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/53 (2006.01) C07D 241/24 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2258752

Compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein E, Q, T, U, V, L, Z, X, W, M, Y and Y' are as set forth herein, are described. These compounds are useful as agents in the treatment of allergy, inflammation, autoimmune diseases, B-cell lymphomas, tumors, and the after effects of bone marrow transplantation.

L'invention concerne des composés représentés par la formule (I), où leurs sels pharmaceutiquement acceptables, E, Q, T, U, V, L, Z, X, W, M, Y et Y' étant définis. Ces composés sont des agents utiles dans le traitement des affections suivantes: allergies, inflammations, maladies auto-immunes, lymphomes malins, tumeurs et effets résiduels de la greffe de moelle osseuse.

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