Narcotine purification process

Details Narcotine purification process Narcotine purification process

C - Chemistry, Metallurgy

07

D

C07D 473/04 (2006.01)

Patent

CA 2649032

A process for purifying Narcotine to remove color and impurities to form Noscapine. The process includes forming an aqueous isopropanol solution with the Narcotine product wherein the isopropanol concentration of the solution is about 20% to about 70% by volume; and adjusting the pH of the solution with a strong base to a pH of about 10 to about 14, wherein impurities are removed from the Narcotine product.

L'invention concerne un procédé de purification de la narcotine destiné à en éliminer la couleur et les impuretés pour former de la noscapine. Le procédé consiste à former une solution aqueuse d'isopropanol avec le produit de narcotine, la concentration en isopropanol de la solution variant d'environ 20% à environ 70% par volume, et à régler le pH de la solution avec une base forte jusqu'à obtenir un pH d'environ 10 à environ 14, les impuretés étant éliminées du produit de narcotine.

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