Naringin and naringenin as 3-hydroxy-3-methylglutaryl...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/35 (2006.01) A23L 1/22 (2006.01) A23L 1/30 (2006.01) A23L 2/52 (2006.01) A23L 2/56 (2006.01) A61K 31/352 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2268437

A pharmaceutical composition for inhibiting the activity of 3-hydroxy-3- methylglutaryl CoA(HMG-CoA) reductase in mammals comprises an effective amount of naringin or naringenin as an active ingredient together with a pharmaceutically acceptable carrier, and a food or beverage composition for inhibiting the 3-hydroxy-3-methylglutaryl CoA(HMG-CoA) reductase activity in mammals comprises an effective amount of naringin or naringenin.

Cette invention se rapporte à une composition pharmaceutique conçue pour inhiber l'activité de la 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG CoA) réductase chez des mammifères, ladite composition contenant une quantité effective de naringine et de naringénine en tant qu'ingrédient actif, dans un excipient pharmaceutiquement acceptable. L'invention se rapporte également à une composition alimentaire ou à une boisson permettant d'inhiber l'activité de la 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG CoA) réductase et contenant une quantité efficace de naringine et de naringénine.

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