Nasal administration of the lh-rh analog leuprolide

Details Nasal administration of the lh-rh analog leuprolide Nasal administration of the lh-rh analog leuprolide

A - Human Necessities

61

K

A61K 38/09 (2006.01) A61K 47/36 (2006.01) A01N 37/18 (2000.01) A61K 38/00 (2000.01)

Patent

CA 2524286

The invention provides a composition for a nasal administration that includes leuprolide and one bioadhesive material that is chitosan. Methods of administration of leuprolide to a mammal suffering from a leuprolide modulated condition, such as endometriosis, prostate cancers, hypogonadism, pre- menstrual syndrome, or uterine leiomyomas.

L'invention concerne une composition pour une administration nasale comprenant du leuprolide et une matière bioadhésive : le chitosane. L'invention concerne des méthodes d'administration de leuprolide à un mammifère souffrant d'un trouble modulé par du leuprolide, notamment une endométriose, des cancers de la prostate, un hypogonadisme, un syndrome pré-menstruel, ou des léiomyomes utérins.

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