Nasal delivery of apomorphine

Details Nasal delivery of apomorphine Nasal delivery of apomorphine

A - Human Necessities

61

K

A61K 31/473 (2006.01) A61K 9/00 (2006.01) A61K 31/00 (2006.01) A61P 15/10 (2006.01)

Patent

CA 2376921

Intranasal delivery methods and compositions for the delivery of dopamine receptor agonists are provided which are effective for the amelioration of erectile dysfunction in a mammal without causing substantial intolerable adverse side effects to the mammal. Nasally administered compositions for treating male erectile dysfunction in a mammal are also provided which include a therapeutically effective amount of a dopamine receptor agonist which has been dispersed in a system to improve its solubility and/or stability.

L'invention porte sur des méthodes et préparations d'administration par voie intranasale d'agonistes du récepteur de la dopamine s'avérant efficaces pour améliorer les troubles de l'érection chez les mammifères sans provoquer d'effets secondaires intolérables notables. L'invention porte également sur des préparations à cet effet contenant une quantité à efficacité thérapeutique d'un agoniste du récepteur de la dopamine dispersé dans un système de manière à en améliorer la solubilité et/ou la stabilité.

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