A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/198 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61K 47/10 (2006.01) A61K 47/26 (2006.01) A61K 47/38 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2426764
There is provided a nateglinide-containing hydrophilic pharmaceutical preparation comprising nateglinide B-type crystals as an effective ingredient, the contact angle of the surface of said preparation to water becoming 111 degree or less by incorporating in said preparation at least one hydrophilic substance selected from the groups consisting of hydrophilic polymers, surfactants, sugars, sugar alcohols and salts. This preparation is one having sufficient immediate-release and high dissolution properties, and can be easily prepared.
L'invention concerne des préparations de médicament contenant des cristaux B de natéglinide comme principe actif, utile en tant qu'agent hypoglycémiant, comprenant un substance hydrophile choisie parmi le groupe comprenant des polymères hydrophiles, des agents tensioactifs, des sucres, des alcools de sucres et des sels, la surface de la préparation faisant ainsi avec l'eau un angle de contact de 111 degrés ou inférieur. Ces préparations, qui sont des préparations à libération rapide avec des propriétés d'élution élevées, peuvent être facilement produites.
Makino Chisato
Ninomiya Nobutaka
Yabuki Akira
Ajinomoto Co. Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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