Natriuretic fusion proteins

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/62 (2006.01) A61K 38/22 (2006.01) C07K 14/575 (2006.01) C07K 14/58 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2689492

Natriuretic peptide fusion proteins comprising natriuretic peptides linked to antibody Fc domains, nucleic acid molecules encoding the fusion proteins disclosed herein, expression vectors expressing said fusion proteins, pharmaceutical compositions comprising said fusion proteins, and methods for their therapeutic use are disclosed.

La présente invention concerne des protéines de fusion de peptides natriurétiques comprenant des peptides natriurétiques liés aux domaines Fc des anticorps, des molécules d'acides nucléiques codant pour les protéines de fusion décrites ici, des vecteurs d'expression exprimant lesdites protéines de fusion, des compositions pharmaceutiques comprenant lesdites protéines de fusion, et des procédés pour leur utilisation thérapeutique.

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