G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/74 (2006.01)
Patent
CA 2736722
The present invention is concerned with a method for predicting the risk of mortality and/or a cardiovascular event in a subject who suffers from the metabolic syndrome based on the determination of a natriuretic peptide and adiponectin in a sample of a subject. Moreover, the present invention relates to a method for identifying a subject being susceptible to a therapy that intends to increase the level of adiponectin in a subject based on the determination of the aforementioned markers. Further comprised by the present invention are kits and devices adapted to carry out the method of the present invention.
L'invention concerne une méthode de prédiction du risque de mortalité et/ou d'événement cardiovasculaire chez un sujet qui souffre du syndrome métabolique, sur la base de la détermination d'un peptide natriurétique et d'adiponectine dans un échantillon du sujet. De plus, l'invention concerne une méthode didentification dun sujet sensible à une thérapie qui a pour but d'augmenter le niveau d'adiponectine chez un sujet, sur la base de la détermination des marqueurs mentionnés ci-dessus. L'invention concerne en outre des kits et dispositifs conçus pour mettre en oeuvre la méthode de la présente invention.
Hess Georg
Horsch Andrea
Zdunek Dietmar
Borden Ladner Gervais Llp
F.hoffmann-La Roche Ag
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