G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/74 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2601959
The present invention relates to a method for diagnosing if a pregnant woman suffers from a cardiac dysfunction, comprising the steps of a) measuring the level of a Natriuretic peptide in a sample b) measuring the level of Placental- growth Factor and/or sFlt-1 or a variant thereof in a sample wherein an increased level of a Natriuretic peptide and a decreased level of Placental-growth Factor and/ or an increased level of sFlt-1 or a variant thereof indicates the presence of a placenta--associated cardiac dysfunction, or wherein an increased level of a Natriuretic peptide and a not decreased level of Placental-growth Factor and/ or a not increased level of sFlt-1 or a variant thereof indicates the presence of a cardiac dysfunction related to heart disease. The present invention also relates to an array, to an immunological rapid test, to the use of corresponding kits and to methods of for a decision support for the possible treatment of a pregnant woman suffering from a cardiac dysfunction.
Hess Georg
Horsch Andrea
Zdunek Dietmar
Borden Ladner Gervais Llp
F. Hoffmann-La Roche Ag
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