Natural biodegradable matrices and uses thereof

Details Natural biodegradable matrices and uses thereof Natural biodegradable matrices and uses thereof

A - Human Necessities

61

L

A61L 31/04 (2006.01) A61L 31/10 (2006.01) A61L 31/14 (2006.01) A61L 31/16 (2006.01)

Patent

CA 2622401

Matrices formed from a natural biodegradable material and that exhibit surface degradation in the presence of an enzyme are described. Matrices including a bioactive agent can be implanted or formed in a subject for release of the bioactive agent upon degradation of the matrix. The matrix can be provided in various forms, including coatings for implantable devices, implants, and in- situ formed matrices. The matrix can also be in the form of a medical device having a structure that is used to treat a medical condition.

L'invention porte sur des matrices formées à partir d'un matériau biodégradable naturel et qui présentent une décomposition superficielle en présence d'un enzyme. Lesdites matrices qui renferment un agent bioactif peuvent être implantées ou formées chez un sujet pour libérer l'agent bioactif lorsque ladite matrice se décompose. La matrice peut se présenter sous des formes diverses, y compris sous la forme de revêtements destinés à des dispositifs implantables, à des implants et à des matrices formées in situ. La matrice peut également se présenter sous la forme d'un dispositif médical disposant d'une structure utilisée pour traiter un état médical.

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