Natural compounds and their derivatives for the prevention...

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 69/16 (2006.01) A61K 31/222 (2006.01) A61P 1/16 (2006.01) A61P 3/02 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) A61P 13/00 (2006.01) A61P 29/00 (2006.01) C07C 69/025 (2006.01)

Patent

CA 2525867

The present invention refers to the use of phenolic compounds and their derivatives represented by formula I wherein R1 and R2 are selected from among: OH, OCOalkyl, or OCOalkenyl, and R3 is either H, OH, OCOalkyl or OCOalkenyl, wherein the alkyl or alkenyl chains present from 2 to 22 carbon atoms and wherein at least one OCOalkyl or OCOalkenyl group is present in the structure, for the prevention and treatment of cardiovascular, hepatic or renal diseases, as well as to their cosmetic applications, to compositions that include these compounds and to some novel phenolic compounds and derivatives. (see formula I)

La présente invention concerne l'utilisation de composés phénoliques et de leurs dérivés, représentés par la formule générale (I), dans laquelle R¿1? et R¿2? désignent des éléments sélectionnés dans le groupe comprenant OH, OCOalkyle ou OCOalcényle, et R¿3? désigne H, OH, OCOalkyle ou OCOalcényle. Dans cette formule, les chaînes alkyle ou alcényle comportent 2 à 22 atomes de carbone et au moins un des groupes OCOalkyle ou OCOalcényle est présent dans la structure. Ces composés sont destinés à la prévention et au traitement de maladies cardiovasculaires, hépatiques et rénales, et ont également des applications cosmétiques. L'invention concerne également des compositions renfermant ces composés et quelques nouveaux composés phénoliques et leurs dérivés.

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