Natural humain igm antibodies

Details Natural humain igm antibodies Natural humain igm antibodies

C - Chemistry, Metallurgy

07

K

C07K 16/10 (2006.01) A61K 39/395 (2006.01) A61K 39/42 (2006.01) C07K 16/18 (2006.01) G01N 33/566 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2134080

The present invention relates to natural human IgM antibodies, and their uses in prognosis, diagnosis, and therapy of HIV infected individuals. In a specific embodiment, the invention relates to low affinity binding natural human serum IgM antibodies. In particular, such antibodies can recognize epitopes present on human protamines, HIV Tat protein and SP80, a seminal plasma homologue of human lactoferrin.

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