Needleless syringe having medical agent accommodated therein

Details Needleless syringe having medical agent accommodated therein Needleless syringe having medical agent accommodated therein

A - Human Necessities

61

M

A61M 5/30 (2006.01) C12N 15/00 (2006.01)

Patent

CA 2525017

A needleless syringe having, accommodated therein, a pharmaceutical preparation containing genes and/or analogues thereof. In particular, a needleless syringe having syringe main body (12) including medical agent chamber (22), the medical agent chamber (22) fitted with one or multiple nozzle bores (25) and having medical agent (L) accommodated therein, and pressure application means (32), the pressure application means (32) capable of applying pressure on the medical agent (L) toward the nozzle bores (25) to thereby effect emission of the medical agent (L) through the nozzle bores (25), wherein the medical agent (L) is a pharmaceutical preparation containing genes and/or analogues thereof. As the medical agent (L), there can be mentioned, for example, a pharmaceutical preparation containing HGF gene and a pharmaceutical preparation containing NF-.kappa.B decoyoligonucleotide.

La présente invention concerne une seringue sans aiguille dans laquelle est contenue une préparation pharmaceutique renfermant des gènes et/ou des analogues de ces derniers. Cette seringue sans aiguille comporte un corps principal (12) de seringue comprenant une chambre (22) pour l'agent thérapeutique, ladite chambre (22) étant dotée d'au moins un orifice de distribution (25) et renfermant un agent thérapeutique (L), ainsi qu'un moyen (32) d'application de pression qui peut appliquer de la pression sur l'agent thérapeutique (L) en direction des orifices de distribution (25) pour assurer la sortie de l'agent thérapeutique (L) par les orifices de distribution (25), ledit agent thérapeutique étant une préparation pharmaceutique contenant des gènes et/ou des analogues de ces derniers. En tant qu'agent thérapeutique (L), on peut par exemple, utiliser une préparation pharmaceutique contenant un gène HGF et une préparation pharmaceutique contenant un oligonucléotide leurre NF-kB.

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