Negatively charged polysaccharide derivable from aloe vera

C - Chemistry – Metallurgy – 08 – B

Patent

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Details

C08B 37/00 (2006.01) A61K 31/715 (2006.01) A61K 31/736 (2006.01) A61K 35/78 (2000.01)

Patent

CA 2471679

A new composition of matter is provided comprising negatively charged polysaccharides which can be derived from Aloe vera and a process to prepare that composition of matter by sub fractionation of an extract of Aloe vera, passing the formed subfraction over a positively charged column and eluting the same with a salt solution. Optionally the Aloe vera is pre purified over a Sephadex G-25 column. This composition of matter and also the extract comprising the same which is formed after pre purification or ultra filtration of an Aloe vera extract is useful as a food supplement or in dietary foods, for use in personal care and in cosmetics, especially to prevent an infection with the bacteria Helicobacter pylori, Pseudomonas aeruginosa, Streptococcus mutans or Streptococcus sanguis.

La présente invention concerne, d'une part une composition à base de polysaccharides à charge négative tirés de l'aloès officinal, et d'autre part un procédé pour l'élaboration de cette composition. En l'occurrence, on réalise un sous-fractionnement d'un extrait d'aloès officinal, on fait passer dans une colonne à charge positive la sous-fraction obtenue, et on en fait une élution avec une solution saline. On peut éventuellement faire une purification préalable de l'aloès officinal dans une colonne à Sephadex G-25. Cette composition ainsi que l'extrait correspondant, obtenus après purification préalable ou ultrafiltration d'un extrait d'aloès officinal conviennent comme compléments alimentaires ou dans des aliments diététiques, pour les soins d'hygiène et la cosmétique, particulièrement pour prévenir l'infection Helicobacter pylori, Pseudomonas aeruginosa, Streptococcus mutans ou Streptococcus sanguis.

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