Neil3 peptides and vaccines including the same

Details Neil3 peptides and vaccines including the same Neil3 peptides and vaccines including the same

C - Chemistry, Metallurgy

12

N

C12N 15/09 (2006.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) C07K 7/06 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2755342

The present invention provides isolated peptides or the fragments derived from SEQ ID NO: 45, which bind to an HLA antigen and induce cytotoxic T lymphocytes (CTL). The peptides may include the above mentioned amino acid sequence with substitution deletion, or addition of one, two, or several amino acids sequences. The invention also provides pharmaceutical compositions including these peptides. The peptides of this invention can be used for diagnosing or treating cancer.

La présente invention porte sur des peptides isolés ou sur les fragments issus de SEQ ID NO: 45, qui se lient à un antigène HLA et induisent des lymphocytes T cytotoxiques (CTL). Les peptides peuvent comprendre la séquence d'acides aminés mentionnée ci-dessus avec substitution, délétion ou addition d'un, deux ou plusieurs séquences d'acides aminés. L'invention porte également des compositions pharmaceutiques comprenant ces peptides. Les peptides de la présente invention peuvent être utilisés pour le diagnostic ou le traitement du cancer.

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