C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 31/7088 (2006.01) A61K 39/095 (2006.01) A61K 39/40 (2006.01) A61K 48/00 (2006.01) C07K 14/22 (2006.01) C07K 16/12 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2346713
The invention provides methods of obtaining immunogenic proteins from genomic sequences including Neisseria, including the amino acid sequences and the corresponding nucleotide sequences, as well as the genomic sequence of Neisseria meningitidis B. The proteins so obtained are useful antigens for vaccines, immunogenic compositions, and/or diagnostics.
L'invention concerne des procédés relatifs à l'élaboration de protéines immunogènes à partir de séquences génomiques, y compris Neisseria, les séquences d'acides aminés et les séquences nucléotidiques correspondantes, ainsi que la séquence génomique de Neisseria meningitidis B. Les protéines résultantes sont des antigènes utiles pour les vaccins, les compositions immunogènes et/ou les opérations de diagnostic.
Fraser Claire M.
Galeotti Cesira
Grandi Guido
Hickey Erin
Masignani Vega
Borden Ladner Gervais Llp
Chiron Corporation
J. Craig Venter Institute Inc.
Novartis Vaccines And Diagnostics Inc.
The Institute For Genomic Research
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