Neisserial vaccine compositions and methods

Details Neisserial vaccine compositions and methods Neisserial vaccine compositions and methods

A - Human Necessities

61

K

A61K 39/095 (2006.01) A61K 39/165 (2006.01) A61K 39/40 (2006.01) A61P 31/04 (2006.01) C07K 14/22 (2006.01) C12N 1/21 (2006.01) C12N 15/31 (2006.01)

Patent

CA 2371928

Methods and compositions for the treatment of microbial infection, and in particular meningococcal disease, comprise a commensal Neisseria or an extract of a commensal Neisseria. Further methods and compositions comprise commensal Neisseria which express genes from virulent strains of Neisseria and/or heterologous gene products from non-neisserial sources. Such compositions are used in vaccine preparations for the treatment of microbial infection.

L'invention concerne des procédés et des compositions permettant de traiter les infections microbiennes, et en particulier la méningococcie. Ces procédés et compositions font appel à un Neisseria commensal ou à un extrait de Neisseria commensal. L'invention concerne d'autres procédés et compositions qui font appel audit Neisseria commensal, exprimant les gènes de souches virulentes de Neisseria et/ou des produits géniques hétérologues de sources autres que le Neisseria. On utilise lesdites compositions dans des préparations de vaccin appropriées au traitement des infections microbiennes.

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