C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/63 (2006.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2498751
This invention pertains to the discovery that the human NELL-1 gene induces or upregulates bone mineralization. The HELL-1 gene or gene product thus provides a convenient target for screening for modulators of bone mineralization. In addition, HELL-1 can be used to facilitate repair of bone fractures and/or to generally increase bone density.
La présente invention a trait à la découverte que le gène <I>NELL-1</I> humain induit ou produit une régulation positive de la minéralisation osseuse. Le gène ou produit génétique NELL-1 procure ainsi une cible appropriée pour le criblage de modulateurs de la minéralisation osseuse. En outre, le gène NELL-1 peut être utilisé pour faciliter la réparation de fractures de l'os et/ou pour accroître de manière générale la densité osseuse.
Fetherstonhaugh & Co.
The Regents Of The University Of California
LandOfFree
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