Nematode phosphoethanolamine n-methyltransferase-like sequences

Details Nematode phosphoethanolamine n-methyltransferase-like sequences Nematode phosphoethanolamine n-methyltransferase-like sequences

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) C07H 21/00 (2006.01) C07K 16/40 (2006.01) C12N 9/10 (2006.01) C12Q 1/48 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2490006

Nucleic acid molecules from nematodes encoding phosphoethanolamine n- methyltransferase polypeptides are described. PEAMT-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PEAMT-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production

Cette invention concerne des molécules d'acides nucléiques tirés de nématodes et codant pour des polypetides de phosphoéthanolamine n-méthyltransférase. L'invention concerne également des séquences polypeptidiques de type PEAMT, ainsi que des vecteurs, cellules hôtes et méthodes de recombinaison pour la production de nucléotides et de polypetides de type PEAMT. Sont en outre décrites des méthodes de criblage permettant d'identifier des inhibiteurs et/ou des activateurs, ainsi que des méthodes de production d'anticorps.

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