Neomorphic ibuprofen and methods of using same

Details Neomorphic ibuprofen and methods of using same Neomorphic ibuprofen and methods of using same

C - Chemistry, Metallurgy

07

C

C07C 57/30 (2006.01) A61K 9/14 (2006.01) A61K 31/19 (2006.01) A61K 31/44 (2006.01) C07C 51/43 (2006.01)

Patent

CA 2166460

A novel neomorphic form of ibuprofen, processes for preparing the ibuprofen, and method for administering the ibuprofen are provided. The neomorphic form is characterized by having a distinctively less bitter taste and causes less burning sensation upon swallowing. The neomorphic form of ibuprofen contains an amorphous ibuprofen. Tests indicate that the neomorphic form is less irritating to the gastrointestinal tract of animals upon administration.

L'invention concerne une nouvelle forme galénique néomorphe de l'ibuprofène, des procédés de préparation de l'ibuprofène et un procédé d'administration de l'ibuprofène. La forme galénique néomorphe se caractérise en ce qu'elle a un goût nettement moins amer et provoque moins de sensation de brûlure lors de la déglutition. La forme galénique néomorphe de l'ibuprofène contient un ibuprofène amorphe. Des tests indiquent que, lors de son administration, la forme galénique néomorphe est moins irritante pour les voies gastro-intestinales des animaux.

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