Neoplasia treatment compositions containing antineoplastic...

A - Human Necessities – 61 – K

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167/100, 167/182

A61K 31/74 (2006.01) A61K 31/785 (2006.01) A61K 45/06 (2006.01) A61K 47/32 (2006.01)

Patent

CA 2014732

C-2557 NEOPLASIA TREATMENT COMPOSITIONS CONTAINING ANTINEOPLASTIC AGENT AND SIDE-EFFECT REDUCING PROTECTIVE AGENT ABSTRACT A combination chemotherapy for treatment of neoplastic diseases is described. Adverse cytotoxic side effects associated with antineoplastic agents may be reduced by the use of a cytoprotective copolymer in combination with the antineoplastic agent. A preferred combination chemotherapy uses doxorubicin to effect tumor remission along with carbetimer as a cytoprotective agent to reduce the toxic side effects associated with doxorubicin and to enhance the antineoplastic activity of doxorubicin.

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