Neothramycin antibiotics from streptomyces

Details Neothramycin antibiotics from streptomyces Neothramycin antibiotics from streptomyces

C - Chemistry, Metallurgy

12

P

195/104, 260/240

C12P 19/44 (2006.01) C07D 487/04 (2006.01) C07G 11/00 (2006.01)

Patent

CA 1056748

NEW ANTIBIOTICS Abstract of the Disclosure There are disclosed two new antibiotics formerly denominated MC916-A and MC916-B and now called neothramycin A and neothramycin B; and their methyl derivates which are potent inhibitors of the growth of leukemia cells, e.g. Leukemia L-1210 cells in mice. They are produced by controlled fermentation of Streptomyces FERM-P 2452 (A.T.C.C. 31123).

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