Neovascular-specific peptides

Details Neovascular-specific peptides Neovascular-specific peptides

C - Chemistry, Metallurgy

07

K

C07K 14/78 (2006.01) A61K 9/127 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) C07K 5/068 (2006.01) C07K 5/097 (2006.01) C07K 7/04 (2006.01) C07K 14/515 (2006.01) C12N 15/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2347136

Neovascular-specific peptides which include, for example, peptides having the amino acid sequences represented by SEQ ID NOS: 1 to 17 and dendrimers thereof. These peptides are applicable to DDS preparations whereby drugs can be delivered selectively to target cancer tissues. Thus these peptides are useful as diagnostics for cancer, remedies for cancer, etc. which contribute to the improvement in the therapeutic effects on cancer.

Peptides spécifiques pour la néovascularisation et consistant, par exemple, en des peptides dont les séquences aminoacides sont représentées par SEQ ID N0S : 1 à 17, et leurs dendrimères. On peut utiliser ces peptides pour des préparations DDS permettant d'administrer de façon sélective des médicaments à des tissus cancéreux ciblés. Ces peptides sont, de ce fait, utiles en diagnostic ou en thérapie du cancer et contribuent à améliorer les effets thérapeutiques permettant de lutter contre le cancer.

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