C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 16/46 (2006.01) C12N 15/63 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2323091
The present invention provides for compositions and methods for detecting susceptibility for basement membrane disease, in particular Congenital nephrotic syndromes of the Finnish type. The present invention for nucleic acids and protein for use in methods and compositions for the diagnosis of disease and identification of small molecule therapeutics for treatment of such disease, in particular of proteinuria associated with kidney disease.
La présente invention concerne des compositions et des procédés de détection de la sensibilité d'un sujet à une maladie de la membrane basale, en particulier le syndrome néphrotique congénital du type finlandais. Cette invention concerne par ailleurs des acides nucléiques et une protéine s'utilisant dans des procédés et des compositions permettant de diagnostiquer cette maladie et d'identifier les agents thérapeutiques constitués de molécules de petites taille destinés à traiter ce type de maladies, en particulier la protéinurie pathologique associée à une maladie rénale.
Kestila Marjo
Lenkkeri Ulla
Mannikko Minna
Tryggvason Karl
Athena Diagnostics Inc.
Biostratum Inc.
Sim & Mcburney
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