Neristatin 1

Details Neristatin 1 Neristatin 1

C - Chemistry, Metallurgy

07

H

C07H 19/01 (2006.01) A61K 31/70 (2006.01) C07D 493/22 (2006.01)

Patent

CA 2074699

ABSTRACT OF THE DISCLOSURE The marine bryozoan Bugula neritina has been found to contain a novel 22-membered macrocyclic lactone which is an inhibitor of lymphocytic leukemia as measured by the US National Cancer Institute's P 388 and in vitro evaluation system. The novel lactone is herein denominated "neristatin 1" and is elucidated. - 12 -

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