Nerve process growth modulators

Details Nerve process growth modulators Nerve process growth modulators

C - Chemistry, Metallurgy

08

B

C08B 37/16 (2006.01) A61K 31/724 (2006.01)

Patent

CA 2257063

Nerve process growth modulation can be achieved using derivatized cyclodextrins. Processes for making sulfated and aminated .beta.-cyclodextrin derivatives are also described in which a compound of the formula R''2 NCH X'+ X'- where R'' is an alkyl containing 1-5 carbon atoms and X' is selected from bromine and iodine is used to halogenate the cyclodextrin.

Il est possible de moduler le processus de croissance des nerfs à l'aide de cyclodextrines transformées en dérivés. L'invention porte également sur un procédé d'obtention de dérivés sulfatés et aminés de la .beta.-cyclodextrine dans lesquels on utilise, pour halogéner la cyclodextrine, un composé de formule R''¿2? NCH X'?+¿ X'?-¿ dans laquelle R'' est un alkyle contenant 1-5 atomes de carbone, et X' est sélectionné entre brome et iode.

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