Neural calcium-activated neutral proteinase inhibitors

Details Neural calcium-activated neutral proteinase inhibitors Neural calcium-activated neutral proteinase inhibitors

C - Chemistry, Metallurgy

07

K

C07K 14/81 (2006.01) A61K 39/395 (2006.01) C07K 16/38 (2006.01) G01N 33/566 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2113202

2113202 9302106 PCTABS00019 This invention is directed to two highly purified neural calcium-activated neutral proteinase (CANP or calpain) inhibitors, known as high molecular weight calpastatin (HMWC) and low molecular weight calpastatin (LMWC). The invention also relates to recombinant DNA molecules which code for, and antibodies which bind to these proteins. The present invention is further directed to the use of these calpastatin proteins.

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