Neural cell adhesion molecule splicing variants

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2243984

NrCAMvar polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing NrCAMvar polypeptides and polynucleotides in the design of protocols for the treatment of diabetes, obesity and cancer, among others, and diagnostic assays for such conditions.

L'invention concerne des polypeptides et des polynucléotides NrCAMvar, ainsi que des procédés de production des ces polypeptides par des techniques de recombinaison. L'invention concerne également des procédés d'utilisation desdits polypeptides et polynucléotides NrCAMvar dans la conception de protocoles destinés notamment au traitement du diabète, de l'obésité, et du cancer, ainsi que dans la conception de méthodes permettant de diagnostiquer ces maladies.

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