A - Human Necessities – 01 – N
Patent
A - Human Necessities
01
N
A01N 63/00 (2006.01) A61K 48/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 1/00 (2006.01) C07K 14/00 (2006.01) C07K 17/00 (2006.01) C12N 15/00 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12N 15/70 (2006.01) C12N 15/74 (2006.01)
Patent
CA 2535753
The present invention features polypeptides having activity of human neurogenin3 (hNgn3), and nucleic acid encoding such polypeptide. The invention also features use of islet transcription factors such as hNgn3 to facilitate production of pancreatic islet cells from progenitor cells, and to facilitate insulin delivery by production of islet cells so produced.
L'invention concerne des polypeptides présentant une activité de neurogénine3 humaine (hNgn3), et un acide nucléique codant un tel polypeptide. L'invention concerne également l'utilisation de facteurs de transcription d'îlots, notamment hNgn3 destinée à faciliter la production de cellules d'îlots pancréatiques à partir de cellules souches, et à faciliter la distribution d'insuline par une production de cellules d'îlots ainsi produites.
Fetherstonhaugh & Co.
The Regents Of The University Of California
LandOfFree
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