C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
530/7.06, 167/10
C07K 7/06 (2006.01) A61K 38/08 (2006.01) C07K 5/02 (2006.01) C07K 7/22 (2006.01) A61K 38/00 (2006.01)
Patent
CA 1340824
Antagonists of neurokinin A which are derivatives of naturally occurring neurokinin A in which the amide bond connecting the two amino acids on the carboxy terminal end is modified are described. The antagonism is confirmed using conventional competitive binding and biochemical assays as well as conventional physiological tests and the use of these derivatives in a variety of conditions in which neurokinin A is implicated is also described.
603179
Buck Stephen H.
Harbeson Scott L.
Hassman Chester F. III
Krstenansky John L.
Mccarthy James R.
Merrell Dow Pharmaceuticals (canada) Inc.
Osler Hoskin & Harcourt Llp
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