Neuromuscular blocking agents

Details Neuromuscular blocking agents Neuromuscular blocking agents

C - Chemistry, Metallurgy

07

D

260/277.3

C07D 217/18 (2006.01) C07D 217/20 (2006.01)

Patent

CA 1113096

ABSTRACT OF THE DISCLOSURE Short acting reversible neuromuscular blocking agents of the formula (I) Image (I) where B and C is preferably meta or maybe para Image where m is 2, 3 or 4, and is preferably 2, R1, R2, R3, R4, R5, R6 and R7 are the same or different and are hydrogen or lower alkoxy of 1 to 4 carbon atoms, Y is lower alkyl of 1 to 4 carbon atoms, n is 2, 3 or 4, most preferably 3, provided that at least one of 3 to R4 and one of R5 to R7 is lower alkoxy and X is a pharmaceutically acceptable anion. These neuromuscular blocking agents of formula I are useful upon administration. to a patient in providing muscular relaxation in the patient during surgery and are normally intravenously administered in a pharmaceutically acceptable carrier.

308434

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